History.
The use of injections
to eliminate abnormal veins dates back more than 100 years. In 1942 Orbach described a method of creating a foam or froth
with the solution he injected. He claimed that this increased the efficacy of injection treatment. This technique was used
by a small number of surgeons but never caught on.
In 1992 Juan Cabrera,
a surgeon from Granada, Spain, found that he could greatly enhance the effect of injection treatment by making a foam of very
small bubbles, which he called 'microfoam'. He used ultrasound imaging to guide his injections into the main surface veins
and found that surgery was unnecessary.
Over the last 6 or
7 years the use of foam injections has spread widely in Europe, South America, and the U.S.
Phlebologists have used a number of different methods to create the foam that they inject but the result is the same:
using a foam greatly increases the effect of the treatment without producing any additional side-effects.
Recently a pharmaceutical
company, Provensis, has commenced development of a commercial foam called 'Varisolve' which is still undergoing clinical trials.
This is specifically intended to treat varicose veins.
What is injected?
The solutions that
are injected are exactly the same as those which are already used to treat varicose veins. These are mixed with air to create
a mousse or microfoam. It has been shown that this is perfectly safe to inject into the veins. The air is rapidly absorbed
from the veins leaving the solution to treat the veins. Sodium tetradecyl sulfate (STS) is the only highly effective
FDA approved sclerosant available in the United States. Polidocanol is widely used in Europe but is in only limited use in
the U.S. because it is not FDA approved. We primarily use STS in our clinics.
Why does foam
work?
When a solution is
injected into a vein it is immediately diluted by the blood, reducing its efficacy. Foam pushes the blood out of the way and
completely fills the vein: the foam is not diluted by the blood. In fact, far less solution has to be injected to obtain the
same effect.
The treatment.